Emerging science shows that mutations in more than 25 different genes may play a role in the development of ALS and that these mutations may be present in people with fALS as well as sALS.
The majority of the total ALS population (around 90%) are estimated to be diagnosed with sALS, and of these, ~10% are estimated to have a genetic component to their disease.
C9orf72, SOD1, TARDBP and FUS mutations (listed in order of decreasing occurrence) have all been found in people with both sALS and fALS.
Speak with your doctor to determine whether you meet the criteria for enrollment in a trial.
People diagnosed with ALS should talk to their doctor about the potential benefits and risks of genetic testing.